Abstract

In sports competitions, bone tissue injury seriously affects athletes’ exercise levels, and some even cause lifelong regrets. With the continuous development of modern medicine, sports medicine has also been rapidly improved, and many tissue engineering techniques have been applied in the field of sports medicine. Used for the treatment of sports injuries, but the repair of bone injuries has always been a thorny issue in the medical field. This article mainly studies the compatibility of composite bio-nanomaterials in the repair of bone tissue damage in sports competitions. The method of constructing bone tissue engineering scaffolds is used to repair bone tissue damage, and the use of protein adsorption and wireless sensor compatibility methods to achieve composite bio-nanomaterials compatible, after 15 days of culture of PCL/PLA/HA nano scaffolds in vitro, stain the protein and observe the binding peptide sequence of the protein, and test the absorbance value. The results of the study showed that the growth rate of surface-bound peptides of nanomaterials was 1.2%, the absorbance value was 540 nm, and the hemolysis value of the experimental group was less than 5%. Biological compatibility is mainly related to the binding peptides on the cell surface, through intracellular and extracellular molecular signal transduction, and has a clear spatiotemporal sequence to optimize bone repair and recovery functions. Therefore, the use of synthetic nanomaterials to repair bone damage is a future trend, and biocompatibility is the key to this research.

摘要

在体育比赛中，骨组织损伤严重影响运动员的运动水平，有的甚至造成终身遗憾。随着现代医学的不断发展，运动医学也得到了迅速的提高，许多组织工程技术已经应用于运动医学领域。用于治疗运动损伤，但骨伤的修复一直是医学领域的棘手问题。本文主要研究复合生物纳米材料在体育比赛骨组织损伤修复中的相容性。采用构建骨组织工程支架的方法修复骨组织损伤，利用蛋白质吸附和无线传感器兼容的方法实现复合生物纳米材料的兼容，PCL/PLA/HA纳米支架体外培养15天后，对蛋白染色，观察蛋白结合肽序列，检测吸光度值。研究结果表明，纳米材料表面结合肽的生长率为1.2%，吸光度值为540 nm，实验组溶血值小于5%。生物相容性主要与细胞表面的结合肽有关，通过细胞内外的分子信号转导，具有明确的时空序列，优化骨修复和恢复功能。因此，利用合成纳米材料修复骨损伤是未来的趋势，而生物相容性是这项研究的关键。并测试吸光度值。研究结果表明，纳米材料表面结合肽的生长率为1.2%，吸光度值为540 nm，实验组溶血值小于5%。生物相容性主要与细胞表面的结合肽有关，通过细胞内外的分子信号转导，具有明确的时空序列，优化骨修复和恢复功能。因此，利用合成纳米材料修复骨损伤是未来的趋势，而生物相容性是这项研究的关键。并测试吸光度值。研究结果表明，纳米材料表面结合肽的生长率为1.2%，吸光度值为540 nm，实验组溶血值小于5%。生物相容性主要与细胞表面的结合肽有关，通过细胞内外的分子信号转导，具有明确的时空序列，优化骨修复和恢复功能。因此，利用合成纳米材料修复骨损伤是未来的趋势，而生物相容性是这项研究的关键。生物相容性主要与细胞表面的结合肽有关，通过细胞内外的分子信号转导，具有明确的时空序列，优化骨修复和恢复功能。因此，利用合成纳米材料修复骨损伤是未来的趋势，而生物相容性是这项研究的关键。生物相容性主要与细胞表面的结合肽有关，通过细胞内外的分子信号转导，具有明确的时空序列，优化骨修复和恢复功能。因此，利用合成纳米材料修复骨损伤是未来的趋势，而生物相容性是这项研究的关键。