A novel nanoreactor containing Cu (II) ions which are well distributed throughout the ionic liquid-based designed layered double hydroxide is applied for azide–alkyne cycloaddition reaction. The synthesized nanocatalyst was fully characterized by thermogravimetry analysis, scanning electron microscopy, X-ray powder diffraction, Fourier transform infrared spectroscopy and Brunauer–Emmett–Teller analysis. The high surface area and the appropriate pore size of the synthesized-nanocatalyst make metal active centers accessible. On the other hand, the presence of ionic liquid in the inner layer of designed hierarchical-functionalized layered double hydroxide nanostructure creates a good environment for the leaching protection and stabilization of extremely dispersed copper ion-containing that results in good reusable features of the nanocatalyst for the synthesis of 1,4-disubstituted-1,2,3-triazole derivatives with excellent yields (75–96%) through an azide-alkyne [3 + 2] cycloaddition reaction.

一种新型纳米反应器含有铜 (II) 离子，这些离子分布在基于离子液体的设计的层状双氢氧化物中，用于叠氮化物-炔烃环加成反应。通过热重分析、扫描电子显微镜、X 射线粉末衍射、傅里叶变换红外光谱和布鲁诺-埃米特-泰勒分析对合成的纳米催化剂进行了全面表征。合成纳米催化剂的高表面积和适当的孔径使金属活性中心易于接近。另一方面，