Abstract

Emerging novel approaches for bone tissue regeneration and engineering are based on bioactive materials scaffolding architectures for mimicking naturally occurring extracellular matrix while also acting as structural platform for cells attachment, multiplication, migration as well as functionalization. Polymeric nano-biocomposites formed from organic/inorganic hybrid biomaterials constructed from comingling of biodegradable polymeric matrices and bioactive inorganic substrates have recently garnered great attention as a result of prevalent efficient performances. Therefore, this paper expounds on state of the art recently emerging trends in bioactive, as well as biodegradable nanocomposites, along with organic/inorganic hybridized biomaterials, in addition to inherent usage for tissue engineering as well as bone regeneration. Emphases are given to nanocomposites oriented on bioactive glasses (BGs) and nanoparticulate hydroxyapatite (nHA)/polymeric matrices (PMs) along with their hybridized components.

摘要

新兴的骨组织再生和工程新方法基于生物活性材料支架结构，用于模拟天然存在的细胞外基质，同时还充当细胞附着、增殖、迁移和功能化的结构平台。由可生物降解的聚合物基质和生物活性无机基质混合而成的有机/无机杂化生物材料形成的聚合物纳米生物复合材料最近由于普遍的高效性能而受到了极大的关注。因此，本文阐述了生物活性和可生物降解纳米复合材料以及有机/无机杂化生物材料的最新发展趋势，以及组织工程和骨再生的固有用途。