Abstract

N-Substituted pyrroles have been prepared in high isolated yields (65–90%) by the reaction of hexane-2,5-dione with amines or diamines in the presence of Fe₃O₄@L-proline@SO₃H at ambient temperature under ultrasonic irradiation and without solvent. The experimental procedure involves simple operations, and the products are readily separated by external magnet. The same reaction of hexane-2,5-dione with amines containing electron-acceptor substituents, such as 4-nitroaniline, resulted in fair yields of pyrrole derivatives.

中文翻译：

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Fe3O4@L-脯氨酸@SO3H作为新型可重复使用的酸性磁性纳米催化剂的合成及其在室温下超声辐照和无溶剂合成N-取代吡咯中的应用

摘要

_{在 Fe 3} O ₄ @ L -proline@SO ₃ H存在下，在环境温度下，己烷-2,5-二酮与胺或二胺反应以高分离产率 (65–90%) 制备了N-取代吡咯超声波辐照和无溶剂下的温度。实验过程操作简单，产品很容易被外磁体分离。己烷-2,5-二酮与含有电子受体取代基的胺（例如 4-硝基苯胺）的相同反应导致吡咯衍生物的收率相当。