We evaluated the effects of a culturally adapted evidence-based HIV prevention intervention (Mpowerment), named “Tayf”, on condom use and HIV testing among young men who have sex with men (YMSM) in Beirut. A 2-year implementation of Tayf was carried out independently and in parallel with a research cohort of 226 YMSM who were surveyed at baseline and months 6, 12, 18 and 24 after Tayf initiation. Primary outcomes were (1) any condomless anal sex with HIV-positive or unknown status partners in the past 3 months, and (2) HIV testing in the past six months. Hierarchical logistic regression models examined the association of Tayf participation with the outcomes averaged across all assessments, and the moderating effect of Tayf participation on change in the outcomes over the follow-up period. A total of 331 YMSM attended at least one event, including 33% of the cohort. Tayf participation was associated with a higher rate of any condomless sex with HIV-positive or unknown status partners averaged across the five assessments, but there was no moderating effect of Tayf participation on change in this outcome over time. Tayf participation was associated with higher HIV testing when averaged across all assessments, but its interaction with time showed that the strength of this association diminished over time. In conclusion, Tayf proved feasible and acceptable in Beirut, but with limited effects. Further work is needed, including innovative publicity and marketing strategies, to bolster effects in high stigma settings where security and legal risks are prominent.

我们评估了一项名为“ Tayf ”的文化适应性循证艾滋病毒预防干预措施 (Mpowerment) 对贝鲁特男男性行为青年 (YMSM) 的安全套使用和艾滋病毒检测的影响。 Tayf的为期 2 年的实施是独立进行的，与 226 名 YMSM 的研究队列同时进行，他们在基线以及Tayf启动后第 6、12、18 和 24 个月进行了调查。主要结果是 (1) 过去 3 个月内与 HIV 阳性或身份不明的伴侣发生过任何无安全套肛交，以及 (2) 过去 6 个月内进行过 HIV 检测。分层逻辑回归模型检查了Tayf参与与所有评估的平均结果之间的关联，以及Tayf参与对随访期间结果变化的调节作用。共有 331 名 YMSM 参加了至少一项活动，占该群体的 33%。在五项评估中， Tayf 的参与与艾滋病毒呈阳性或身份不明的伴侣进行无安全套性行为的比例较高有关，但随着时间的推移， Tayf的参与对该结果的变化没有调节作用。当对所有评估进行平均时， Tayf参与与较高的 HIV 检测相关，但其与时间的相互作用表明，这种关联的强度随着时间的推移而减弱。总之，泰夫在贝鲁特被证明是可行和可接受的，但效果有限。需要开展进一步的工作，包括创新的宣传和营销策略，以增强在安全和法律风险突出的高耻辱环境中的效果。