PURPOSE To assess the effect of decentration and tilt combined with prior myopic ablations on the optical performance of a trifocal intraocular lens (IOL) and a novel IOL with an extended depth of focus (EDOF) design. METHODS The XACT Mono-EDOF ME4 (Santen Pharmaceutical Co Ltd) and the trifocal FineVision (PhysIOL) IOLs were analyzed with and without simulated previous myopic ablations. The optical quality of the IOLs was evaluated with the PMTF optical bench (LAMBDA-X). The through-focus modulation transfer function (MTF) curves were recorded. Measurements were done for three situations: centered, 0.4 mm decentered, and 4 degrees tilted. RESULTS The trifocal IOL showed three peaks of vision and the EDOF IOL showed a far distance peak with intermediate addition. When decentration or tilt were induced, the trifocal IOL showed negligible changes but the EDOF IOL showed a -0.50 diopters (D) shift of the overall curve. With simulated myopic ablation, the trifocal IOL showed a -0.50 D shift of the curve. When tilt or decentration were also induced, the better optical results were found at -1.00 D. With myopic ablations, the EDOF IOL showed a -0.50 D shift of the optical quality and when decentration or tilt were then induced, negative shifts over -1.00 D were found. CONCLUSIONS The trifocal IOL was less affected by mis-alignments. When myopic ablations were induced, both lenses decreased their optical quality and the effects of misalignments were higher. In patients who have undergone corneal myopic ablation procedures, proper alignment of the implanted IOL and obtaining effective emmetropia becomes even more critical. [J Refract Surg. 2021;37(8):532-537.].

中文翻译：

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三焦人工晶状体的倾斜和偏心以及角膜近视消融眼的新型焦深人工晶状体的倾斜和偏心引起的光学质量变化。

目的 评估偏心和倾斜结合先前的近视消融对三焦点人工晶状体 (IOL) 和具有扩展焦深 (EDOF) 设计的新型人工晶状体的光学性能的影响。方法 XACT Mono-EDOF ME4 (Santen Pharmaceutical Co Ltd) 和三焦 FineVision (PhysIOL) 人工晶状体在有和没有模拟的先前近视消融的情况下进行了分析。人工晶状体的光学质量使用 PMTF 光学平台 (LAMBDA-X) 进行评估。记录离焦调制传递函数 (MTF) 曲线。测量针对三种情况进行：居中、0.4 毫米偏心和 4 度倾斜。结果 三焦人工晶状体呈现三个视力峰值，EDOF人工晶状体呈现远距离峰值，中间加样。当引起偏心或倾斜时，三焦人工晶状体的变化可以忽略不计，但 EDOF 人工晶状体的整体曲线有 -0.50 屈光度 (D) 偏移。通过模拟近视消融，三焦人工晶状体显示出 -0.50 D 的曲线偏移。当还引起倾斜或偏心时，在 -1.00 D 处发现更好的光学结果。对于近视消融，EDOF IOL 显示出 -0.50 D 的光学质量偏移，然后当引起偏心或倾斜时，负偏移超过 -1.00 D 被发现。结论 三焦人工晶状体受错位影响较小。当诱发近视消融时，两个镜片的光学质量都会降低，错位的影响更大。在接受角膜近视消融手术的患者中，植入的人工晶状体的正确对齐和获得有效的正视变得更加重要。[J 屈光手术。2021；37(8)：