We read with great interest the work reported by Yoon et al. [1]. The authors found that a high concentration of nitrogen dioxide at an individual's residential address is significantly associated with increased mortality in idiopathic pulmonary fibrosis (IPF) patients when all confounders are included in the health analysis model. However, an important question that remains unclear in the study is whether active or passive cigarette smoking-associated release of nitrogen dioxide or particulate matter plays a role in the clinical outcome of IPF patients.

中文翻译：

---

吸烟产生的污染物在特发性肺纤维化死亡风险中的作用

我们饶有兴趣地阅读了Y报道的工作恩等人。 [1]。作者发现，当所有混杂因素都包含在健康分析模型中时，个人居住地址的高浓度二氧化氮与特发性肺纤维化（IPF）患者的死亡率增加显着相关。然而，该研究中仍不清楚的一个重要问题是主动或被动吸烟相关的二氧化氮或颗粒物的释放是否在IPF患者的临床结果中发挥作用。