Objective: Generalized anxiety disorder (GAD) is a debilitating condition, characterized by negative interpretations about ambiguous situations. This study tested whether entirely internet-delivered interpretation training [cognitive bias modification (CBM)] versus control promotes positive interpretations and reduces worry and anxiety in individuals with GAD, with or without depression. Method: A two-arm (CBM; control) parallel-group randomized controlled experiment. Assessments were preintervention (T0), postintervention (T1), 1-month (T2) postintervention, and 3-month (T3) postintervention. Participants with GAD (with or without comorbid depression) were randomly allocated to either CBM (n = 115) or control (n = 115). Participants, but not researchers, were blind to allocated condition. Participants completed up to 10 online CBM or control sessions across 1 month. Interpretation bias [coprimary outcomes: scrambled sentence test (SST), recognition test (RT)], and number of negative thought intrusions during a breathing focus task were measured at T0 and T1. Self-reported levels of worry [Penn State Worry Questionnaire-trait (PSWQ trait); Penn State Worry Questionnaire-past week (PSWQ weekly)], anxiety [Generalized Anxiety Disorder scale (GAD-7)], depression [Patient Health Questionnaire (PHQ-9)], rumination [Ruminative Response Scale (RRS)], and repetitive negative thinking [RNT; Repetitive Thinking Questionnaire-trait (RTQ-trait)] were assessed at T0-T3. Results: The per-protocol analyses included N = 186 participants (CBM n = 94; control n = 92). As predicted, we found moderate-to-large training effects on the primary outcome of interpretation bias at T1. Secondary outcomes of negative thought intrusions at T1 and self-reported symptoms at T2 were all significantly lower in the CBM versus control condition. All but one effect (trait RNT) were sustained at T3. Conclusions: In this randomized controlled study, we found that fully online interpretation training ameliorated core features of GAD in individuals with or without comorbid depression up to 3 months posttraining. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

中文翻译：

---

互联网提供的口译培训减少了广泛性焦虑症患者的担忧和焦虑：一项随机对照实验。

目的：广泛性焦虑症 (GAD) 是一种使人衰弱的疾病，其特征是对模棱两可的情况产生负面解释。这项研究测试了完全通过互联网提供的口译训练 [认知偏差修正 (CBM)] 与控制相比，是否能促进积极的口译并减少 GAD 患者（无论是否患有抑郁症）的担忧和焦虑。方法：两臂（CBM；对照）平行组随机对照实验。评估为干预前 (T0)、干预后 (T1)、干预后 1 个月 (T2) 和干预后 3 个月 (T3)。患有 GAD（有或没有共病抑郁症）的参与者被随机分配到 CBM（n = 115）或对照组（n = 115）。参与者，但不是研究人员，对分配的条件视而不见。参与者在 1 个月内完成了多达 10 个在线 CBM 或控制会话。在 T0 和 T1 测量了解释偏差 [共同主要结果：乱句测试 (SST)、识别测试 (RT)] 和呼吸焦点任务期间消极思想侵入的次数。自我报告的担忧程度 [宾夕法尼亚州立大学担忧问卷特征（PSWQ 特征）；Penn State Worry Questionnaire-过去一周（PSWQ 每周）]、焦虑 [广泛性焦虑障碍量表 (GAD-7)]、抑郁 [患者健康问卷 (PHQ-9)]、沉思 [反刍反应量表 (RRS)] 和重复消极思维 [RNT; 重复思维问卷-特质（RTQ-特质）] 在 T0-T3 进行评估。结果：符合方案的分析包括 N = 186 名参与者（CBM n = 94；对照 n = 92）。正如预测的那样，我们发现训练对 T1 解释偏差的主要结果有中到大的影响。在 CBM 与对照条件下，T1 时消极思想侵入和 T2 时自我报告症状的次要结果都显着降低。除了一种效应（性状 RNT）外，所有效应都在 T3 时持续存在。结论：在这项随机对照研究中，我们发现完全在线的口译训练在训练后 3 个月内改善了患有或不患有共病抑郁症的个体 GAD 的核心特征。（PsycInfo 数据库记录 (c) 2021 APA，保留所有权利）。在这项随机对照研究中，我们发现完全在线的口译训练在训练后 3 个月内改善了患有或不患有共病抑郁症的个体 GAD 的核心特征。（PsycInfo 数据库记录 (c) 2021 APA，保留所有权利）。在这项随机对照研究中，我们发现完全在线的口译训练在训练后 3 个月内改善了患有或不患有共病抑郁症的个体 GAD 的核心特征。（PsycInfo 数据库记录 (c) 2021 APA，保留所有权利）。