Abscission is the second stage of cytokinesis. Cep55, a coiled-coil protein, is thought to recruit endosomal sorting complexes required for transport (ESCRTs) to the midbody to complete abscission. However, recent studies of Cep55-knockout mice reveal that most cells can complete abscission without Cep55. More work is needed to understand abscission mechanisms in different cell types.

中文翻译：

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Cep55：离职老板还是助理？

脱落是胞质分裂的第二阶段。Cep55 是一种卷曲螺旋蛋白，被认为将转运所需的内体分选复合物 (ESCRT) 募集到中间体以完成脱落。然而，最近对Cep55敲除小鼠的研究表明，大多数细胞可以在没有 Cep55 的情况下完成脱落。需要做更多的工作来了解不同细胞类型的脱落机制。