Atherosclerosis causes myocardial infarction, ischaemic cardiomyopathy, many ischaemic strokes and jeopardized limbs. Despite enormous progress, atherosclerosis has become the major cause of death worldwide. This Comment intertwines clinical and basic advances in atherosclerosis to illustrate their interdependence, which provides a template for a way forwards to conquer the scourge of atherosclerotic cardiovascular disease.

中文翻译：

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动脉粥样硬化的生物学来了一个完整的循环：征服心血管疾病的教训

动脉粥样硬化导致心肌梗塞、缺血性心肌病、许多缺血性中风和危及肢体。尽管取得了巨大的进步，但动脉粥样硬化已成为全世界死亡的主要原因。这篇评论将动脉粥样硬化的临床和基本进展交织在一起，以说明它们之间的相互依赖关系，为克服动脉粥样硬化性心血管疾病的祸害提供了一个模板。