Children with a family history of hypertension have higher blood pressure and hypertensive pathophysiological changes begin before clinical findings. Here, the presence of arterial stiffness was investigated using central blood pressure measurement and pulse wave analysis in normotensive children with at least one parent with essential hypertension. Twenty-four-hour ambulatory pulse wave analysis monitoring was performed by oscillometric method in a study group of 112 normotensive children of hypertensive parents aged between 7 and 18 comparing with a control group of 101 age- and gender-matched normotensive children of normotensive parents. Pulse wave velocity, central systolic and diastolic blood pressure, systolic, diastolic and mean arterial blood pressure values were higher in the study group than the control group (p < 0.001, p = 0.002, p = 0.008, p = 0.001, p = 0.005, p = 0.001, p = 0.001, respectively). In all age groups (7–10, 11–14, and 15–18 years), pulse wave velocity was higher in the study group than the control group (p < 0.001). Pulse wave velocity was higher in children whose both parents are hypertensive compared to the children whose only mothers are hypertensive (p = 0.011). Pulse wave velocity values were positively correlated with age, weight, height, and body mass index (p < 0.05). Higher pulse wave velocity, central systolic and diastolic blood pressure values detected in the study group can be considered as early signs of hypertensive vascular changes. Pulse wave analysis can be a reliable, non-invasive, and reproducible method that can allow taking necessary precautions regarding lifestyle to prevent disease and target organ damage by detecting early hypertensive changes in genetically risky children.

有高血压家族史的儿童血压较高，高血压病理生理变化在临床发现之前就开始了。在这里，使用中心血压测量和脉搏波分析在至少有一位父母患有原发性高血压的血压正常儿童中研究动脉僵硬度的存在。24 小时动态脉搏波分析监测采用示波法对 112 名年龄在 7 至 18 岁的高血压父母的正常血压儿童进行比较，对照组为 101 名年龄和性别匹配的血压正常儿童的正常血压父母。研究组的脉搏波速度、中心收缩压和舒张压、收缩压、舒张压和平均动脉血压值均高于对照组（p < 0.001，p = 0.002，p = 0.008、p = 0.001、p = 0.005、p = 0.001、p = 0.001）。在所有年龄组（7-10、11-14 和 15-18 岁）中，研究组的脉搏波速度均高于对照组（p < 0.001）。与唯一母亲患有高血压的儿童相比，父母双方都患有高血压的儿童的脉搏波速度更高（p = 0.011）。脉搏波速度值与年龄、体重、身高和体重指数呈正相关（p < 0.05）。在研究组中检测到的较高脉搏波速度、中心收缩压和舒张压值可以被认为是高血压血管变化的早期迹象。脉搏波分析可以是一种可靠的、非侵入性的、