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Breakthrough invasive fungal infections in liver transplant recipients exposed to prophylaxis with echinocandins vs other antifungal agents: A systematic review and meta-analysis
Mycoses ( IF 4.1 ) Pub Date : 2021-08-12 , DOI: 10.1111/myc.13362
Milo Gatti 1, 2 , Matteo Rinaldi 3 , Giuseppe Ferraro 3 , Alice Toschi 3 , Natascia Caroccia 3 , Federica Arbizzani 3 , Emanuel Raschi 1 , Elisabetta Poluzzi 1 , Federico Pea 1, 2 , Pierluigi Viale 1, 3 , Maddalena Giannella 1, 3
Affiliation  

Although echinocandins are recommended as first-line prophylaxis for high-risk orthotopic liver transplant (OLT) recipients, occurrence of breakthrough-invasive fungal infections (IFIs) remains a serious concern. We aim to assess the risk of breakthrough IFIs among OLT recipients exposed to prophylaxis with echinocandins compared to other antifungals.

中文翻译:

暴露于棘白菌素与其他抗真菌剂预防的肝移植受者的突破性侵袭性真菌感染:系统评价和荟萃分析

尽管棘白菌素被推荐作为高危原位肝移植 (OLT) 受者的一线预防药物,但突破性侵袭性真菌感染 (IFI) 的发生仍然是一个严重问题。我们旨在评估与其他抗真菌剂相比,在接触棘白菌素预防的 OLT 接受者中发生突破性 IFI 的风险。
更新日期:2021-10-20
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