PURPOSE To determine changes and potential differences in physical activity (PA), gross motor proficiency (MP), and health parameters after a 6-month follow-up (FU) period following participation in a parent-led PA intervention in youth with or without Prader-Willi syndrome (PWS). METHODS About 42 youth with PWS and 65 youth without PWS but with obesity (body fat percentage >95th percentile for age and sex), aged 8-16 years, participated. The intervention included preplanned PA sessions containing playground and console-based video games scheduled 4 days per week for 24 weeks. Families received training and curriculum materials. PA (accelerometry), MP (Bruininks-Oseretsky Test of MP), and health-related quality of life were obtained before (PRE), after completing the intervention (POST), and at FU. RESULTS There were no significant changes in PA at any time point. At FU and POST, participants showed higher bilateral coordination (PRE = 9.3 [0.4], POST = 11.7 [0.5], and FU = 11.1 [0.6]); speed and agility (PRE = 9.2 [0.4], POST = 10.8 [0.4], and FU = 11.5 [0.5]); and strength (PRE = 8.0 [0.3], POST = 9.2 [0.3], and FU = 9.2 [0.3]) than at PRE. At FU (80.3 [2.1]) and POST (79.8 [1.7]), youth without PWS showed higher health-related quality of life than PRE (75.0 [1.8]). CONCLUSION The improvements in MP and health-related quality of life at FU suggest long-term durability of intervention outcomes.

中文翻译：

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在完成家长主导的基于游戏的干预 6 个月后，改善了患有 Prader-Willi 综合征和肥胖症的青年的运动能力和生活质量。

目的 确定在有或没有参加父母主导的 PA 干预后的 6 个月随访 (FU) 后身体活动 (PA)、粗大运动能力 (MP) 和健康参数的变化和潜在差异Prader-Willi 综合征 (PWS)。方法 大约 42 名患有 PWS 的青年和 65 名没有 PWS 但肥胖的青年（体脂百分比> 年龄和性别的第 95 个百分位）参加，年龄在 8-16 岁。干预包括预先计划的 PA 课程，其中包括每周 4 天、持续 24 周的游乐场和基于控制台的视频游戏。家庭接受了培训和课程材料。PA（加速度计）、MP（Bruininks-Oseretsky MP 测试）和健康相关的生活质量在干预前（PRE）、干预完成后（POST）和 FU 获得。结果 在任​​何时间点，PA 均无显着变化。在 FU 和 POST，参与者表现出更高的双边协调性（PRE = 9.3 [0.4]，POST = 11.7 [0.5] 和 FU = 11.1 [0.6]）；速度和敏捷性（PRE = 9.2 [0.4]、POST = 10.8 [0.4] 和 FU = 11.5 [0.5]）；和强度（PRE = 8.0 [0.3]，POST = 9.2 [0.3] 和 FU = 9.2 [0.3]）比 PRE。在 FU (80.3 [2.1]) 和 POST (79.8 [1.7]) 中，没有 PWS 的青年表现出比 PRE (75.0 [1.8]) 更高的健康相关生活质量。结论 FU MP 和健康相关生活质量的改善表明干预结果的长期持久性。0 [0.3]、POST = 9.2 [0.3] 和 FU = 9.2 [0.3]）比在 PRE 时。在 FU (80.3 [2.1]) 和 POST (79.8 [1.7]) 中，没有 PWS 的青年表现出比 PRE (75.0 [1.8]) 更高的健康相关生活质量。结论 FU MP 和健康相关生活质量的改善表明干预结果的长期持久性。0 [0.3]、POST = 9.2 [0.3] 和 FU = 9.2 [0.3]）比在 PRE 时。在 FU (80.3 [2.1]) 和 POST (79.8 [1.7]) 中，没有 PWS 的青年表现出比 PRE (75.0 [1.8]) 更高的健康相关生活质量。结论 FU MP 和健康相关生活质量的改善表明干预结果的长期持久性。