Inter-subject stability and regional concentration estimates of 3D-FID-MRSI in the human brain at 7 T,NMR in Biomedicine

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Inter-subject stability and regional concentration estimates of 3D-FID-MRSI in the human brain at 7 T
NMR in Biomedicine ( IF 2.7 ) Pub Date : 2021-08-11 , DOI: 10.1002/nbm.4596
Gilbert Hangel _{1,

2} , Benjamin Spurny-Dworak ₃ , Philipp Lazen ₁ , Cornelius Cadrien _{1,

2} , Sukrit Sharma ₁ , Lukas Hingerl ₁ , Eva Hečková ₁ , Bernhard Strasser ₁ , Stanislav Motyka ₁ , Alexandra Lipka _{1,

4} , Stephan Gruber ₁ , Christoph Brandner ₅ , Rupert Lanzenberger ₃ , Karl Rössler ₂ , Siegfried Trattnig _{1,

4} , Wolfgang Bogner ₁

Affiliation

Recently, a 3D-concentric ring trajectory (CRT)-based free induction decay (FID)-MRSI sequence was introduced for fast high-resolution metabolic imaging at 7 T. This technique provides metabolic ratio maps of almost the entire brain within clinically feasible scan times, but its robustness has not yet been thoroughly investigated. Therefore, we have assessed quantitative concentration estimates and their variability in healthy volunteers using this approach.

中文翻译：

7 T 时人脑中 3D-FID-MRSI 的受试者间稳定性和区域浓度估计

最近，引入了基于 3D 同心环轨迹 (CRT) 的自由感应衰减 (FID)-MRSI 序列，用于在 7 T 下进行快速高分辨率代谢成像。该技术在临床可行的扫描中提供了几乎整个大脑的代谢比率图次，但其鲁棒性尚未得到彻底研究。因此，我们使用这种方法评估了健康志愿者的定量浓度估计值及其变异性。

更新日期：2021-08-11

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