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Organization of Parieto-Prefrontal and Temporo-Prefrontal Networks in the Macaque
Journal of Neurophysiology ( IF 2.5 ) Pub Date : 2021-08-11 , DOI: 10.1152/jn.00092.2021
Franco Giarrocco 1 , Bruno B Averbeck 1
Affiliation  

The connectivity among architectonically defined areas of the frontal, parietal, and temporal cortex of the macaque has been extensively mapped through tract tracing methods. To investigate the statistical organization underlying this connectivity, and identify its underlying architecture, we performed a hierarchical cluster analysis on 69 cortical areas based on their anatomically defined inputs. We identified 10 frontal, 4 parietal, and 5 temporal hierarchically related sets of areas (clusters), defined by unique sets of inputs and typically composed of anatomically contiguous areas. Across cortex, clusters that share functional properties were linked by dominant information processing circuits in a topographically organized manner that reflects the organization of the main fiber bundles in the cortex. This led to a dorsal-ventral subdivision of the frontal cortex, where dorsal and ventral clusters showed privileged connectivity with parietal and temporal areas, respectively. Ventrally, temporo-frontal circuits encode information to discriminate objects in the environment, their value, emotional properties, and functions such as memory and spatial navigation. Dorsal parieto-frontal circuits encode information for selecting, generating, and monitoring appropriate actions based on visual-spatial and somatosensory information. This organization may reflect evolutionary antecedents, in which the vertebrate pallium, which is the ancestral cortex, was defined by a ventral and lateral olfactory region and a medial hippocampal region.

中文翻译:

猕猴顶前额叶和颞叶前额叶网络的组织

猕猴额叶、顶叶和颞叶皮层的结构定义区域之间的连通性已通过轨迹追踪方法广泛绘制。为了研究这种连通性背后的统计组织,并确定其基础架构,我们根据解剖学定义的输入对 69 个皮质区域进行了层次聚类分析。我们确定了 10 个额叶、4 个顶叶和 5 个时间层次相关的区域集(集群),由独特的输入集定义,通常由解剖学上连续的区域组成。在整个皮层,共享功能特性的簇通过主要的信息处理电路以一种拓扑组织的方式连接起来,这种方式反映了皮层中主要纤维束的组织。这导致了额叶皮层的背腹细分,其中背侧和腹侧簇分别显示出与顶叶和颞叶区域的特权连接。在腹侧,颞叶回路对信息进行编码,以区分环境中的物体、它们的价值、情感属性以及记忆和空间导航等功能。背顶额叶回路对信息进行编码,用于根据视觉空间和体感信息选择、生成和监控适当的动作。这种组织可能反映了进化的前身,其中脊椎动物的大脑皮层,即祖先皮层,由腹侧和外侧嗅觉区域以及内侧海马区域定义。分别。在腹侧,颞叶回路对信息进行编码,以区分环境中的物体、它们的价值、情感属性以及记忆和空间导航等功能。背顶额叶回路对信息进行编码,用于根据视觉空间和体感信息选择、生成和监控适当的动作。这种组织可能反映了进化的前身,其中脊椎动物的大脑皮层,即祖先皮层,由腹侧和外侧嗅觉区域以及内侧海马区域定义。分别。在腹侧,颞叶回路对信息进行编码,以区分环境中的物体、它们的价值、情感属性以及记忆和空间导航等功能。背顶额叶回路对信息进行编码,用于根据视觉空间和体感信息选择、生成和监控适当的动作。这种组织可能反映了进化的前身,其中脊椎动物的大脑皮层,即祖先皮层,由腹侧和外侧嗅觉区域以及内侧海马区域定义。并根据视觉空间和体感信息监测适当的行动。这种组织可能反映了进化的前身,其中脊椎动物的大脑皮层,即祖先皮层,由腹侧和外侧嗅觉区域以及内侧海马区域定义。并根据视觉空间和体感信息监测适当的行动。这种组织可能反映了进化的前身,其中脊椎动物的大脑皮层,即祖先皮层,由腹侧和外侧嗅觉区域以及内侧海马区域定义。
更新日期:2021-08-12
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