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CBC-Clock Theory of Life – Integration of cellular circadian clocks and cellular sentience is essential for cognitive basis of life
BioEssays ( IF 3.2 ) Pub Date : 2021-08-11 , DOI: 10.1002/bies.202100121 František Baluška 1 , Arthur S Reber 2
BioEssays ( IF 3.2 ) Pub Date : 2021-08-11 , DOI: 10.1002/bies.202100121 František Baluška 1 , Arthur S Reber 2
Affiliation
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Cellular circadian clocks represent ancient anticipatory systems which co-evolved with the first cells to safeguard their survival. Cyanobacteria represent one of the most ancient cells, having essentially invented photosynthesis together with redox-based cellular circadian clocks some 2.7 billion years ago. Bioelectricity phenomena, based on redox homeostasis associated electron transfers in membranes and within protein complexes inserted in excitable membranes, play important roles, not only in the cellular circadian clocks and in anesthetics-sensitive cellular sentience (awareness of environment), but also in the coupling of single cells into tissues and organs of unitary multicellular organisms. This integration of cellular circadian clocks with cellular basis of sentience is an essential feature of the cognitive CBC-Clock basis of cellular life.
中文翻译：
CBC-生命时钟理论——细胞生物钟和细胞感知的整合对于生命的认知基础至关重要
细胞生物钟代表了古老的预期系统，它与第一批细胞共同进化以保护它们的生存。蓝藻是最古老的细胞之一，大约在 27 亿年前，它们基本上发明了光合作用和基于氧化还原的细胞生物钟。生物电现象，基于氧化还原稳态相关的膜中和插入可兴奋膜的蛋白质复合物中的电子转移，不仅在细胞生物钟和麻醉剂敏感的细胞感知（环境意识）中，而且在耦合中发挥重要作用将单个细胞转化为单一多细胞生物的组织和器官。
更新日期：2021-09-27
中文翻译：
CBC-生命时钟理论——细胞生物钟和细胞感知的整合对于生命的认知基础至关重要
细胞生物钟代表了古老的预期系统，它与第一批细胞共同进化以保护它们的生存。蓝藻是最古老的细胞之一，大约在 27 亿年前，它们基本上发明了光合作用和基于氧化还原的细胞生物钟。生物电现象，基于氧化还原稳态相关的膜中和插入可兴奋膜的蛋白质复合物中的电子转移，不仅在细胞生物钟和麻醉剂敏感的细胞感知（环境意识）中，而且在耦合中发挥重要作用将单个细胞转化为单一多细胞生物的组织和器官。
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