A nano perspective behind the COVID-19 pandemic,Nanoscale Horizons

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A nano perspective behind the COVID-19 pandemic
Nanoscale Horizons ( IF 8.0 ) Pub Date : 2021-08-04 , DOI: 10.1039/d1nh00135c
Camila Pedroso Silveira ₁ , Andressa da Cruz Schneid ₁ , Iris Renata Sousa Ribeiro _{1,

2} , Flávia Elisa Galdino _{1,

2} , Mateus Borba Cardoso _{1,

2}

Affiliation

The global pandemic scenario has definitely pushed the scientific community to develop COVID-19 vaccines at unprecedented speed. Nevertheless, a worldwide vaccination campaign is still far from being achieved, making the usual precautionary measures as necessary as at the beginning of the outbreak. Many aspects of the SARS-CoV-2 infectious potential and disease severity do not solely rely on interactions at the molecular level but also on physical–chemical parameters that often involve nanoscale effects. Here the SARS-CoV-2 journey to infect a susceptible host is reviewed, focusing on the nanoscale aspects that play a role in the viral infectivity and disease progression. These nanoscale-driven interactions are essential to establish mitigation-related strategies.

中文翻译：

COVID-19 大流行背后的纳米视角

全球大流行的情况无疑促使科学界以前所未有的速度开发 COVID-19 疫苗。尽管如此，全球疫苗接种运动仍远未实现，这使得通常的预防措施与爆发初期一样必要。SARS-CoV-2 感染潜力和疾病严重程度的许多方面不仅依赖于分子水平上的相互作用，还依赖于通常涉及纳米级效应的物理化学参数。这里回顾了 SARS-CoV-2 感染易感宿主的过程，重点关注在病毒感染性和疾病进展中发挥作用的纳米级方面。这些纳米级驱动的相互作用对于建立与缓解相关的策略至关重要。

更新日期：2021-08-12

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