The current manufacturing solutions for oral solid dosage forms are fundamentally based on technologies from the 19th century. This approach is well suited for mass production of one-size-fits-all products; however, it does not allow for a straight-forward personalization and mass customization of the pharmaceutical end-product. In order to provide better therapies to the patients, a need for innovative manufacturing concepts and product design principles has been rising. Additive manufacturing opens up a possibility for compartmentalization of drug products, including design of spatially separated multidrug and functional excipient compartments. This compartmentalized solution can be further expanded to modular design thinking. Modular design is referring to combination of building blocks containing a given amount of drug compound(s) and related functional excipients into a larger final product. Implementation of modular design principles is paving the way for implementing the emerging personalization potential within health sciences by designing compartmental and reactive product structures that can be manufactured based on the individual needs of each patient. This review will introduce the existing compartmentalized product design principles and discuss the integration of these into edible electronics allowing for innovative control of drug release.

目前口服固体剂型的制造解决方案基本上是基于 19 世纪的技术。这种方法非常适合大规模生产一刀切的产品；但是，它不允许对医药最终产品进行直接的个性化和大规模定制。为了给患者提供更好的治疗，对创新制造理念和产品设计原则的需求不断上升。增材制造为药物产品的划分开辟了可能性，包括空间分离的多药和功能性赋形剂隔间的设计。这种划分的解决方案可以进一步扩展到模块化设计思维。模块化设计是指将含有给定量药物化合物和相关功能性辅料的构件组合成更大的最终产品。模块化设计原则的实施通过设计可根据每个患者的个体需求制造的隔间和反应性产品结构，为在健康科学中实现新兴的个性化潜力铺平了道路。这篇综述将介绍现有的分区产品设计原则，并讨论将这些原则整合到可食用电子产品中，从而实现对药物释放的创新控制。模块化设计原则的实施通过设计可根据每个患者的个体需求制造的隔间和反应性产品结构，为在健康科学中实现新兴的个性化潜力铺平了道路。本综述将介绍现有的分区产品设计原则，并讨论将这些原则整合到可食用电子产品中，从而实现对药物释放的创新控制。模块化设计原则的实施通过设计可根据每个患者的个体需求制造的隔间和反应性产品结构，为在健康科学中实现新兴的个性化潜力铺平了道路。这篇综述将介绍现有的分区产品设计原则，并讨论将这些原则整合到可食用电子产品中，从而实现对药物释放的创新控制。