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Functional connectivity changes in complex migraine aura: beyond the visual network
European Journal of Neurology ( IF 5.1 ) Pub Date : 2021-08-12 , DOI: 10.1111/ene.15061
Marcello Silvestro 1, 2 , Alessandro Tessitore 1, 2 , Federica Di Nardo 2 , Fabrizio Scotto di Clemente 1, 2 , Francesca Trojsi 1, 2 , Mario Cirillo 1, 2 , Fabrizio Esposito 2 , Gioacchino Tedeschi 1, 2 , Antonio Russo 1, 2
Affiliation  

Although the majority of migraine with aura (MwA) patients experience simple visual aura, a discrete percentage also report somatosensory, dysphasic or motor symptoms (the so-called complex auras). The wide aura clinical spectrum led to an investigation of whether the heterogeneity of the aura phenomenon could be produced by different neural correlates, suggesting an increased visual cortical excitability in complex MwA. The aim was to explore whether complex MwA patients are characterized by more pronounced connectivity changes of the visual network and whether functional abnormalities may extend beyond the visual network encompassing also the sensorimotor network in complex MwA patients compared to simple visual MwA patients.

中文翻译:

复杂偏头痛先兆的功能连接变化:超越视觉网络

尽管大多数先兆偏头痛 (MwA) 患者会出现简单的视觉先兆,但也有少数人报告有躯体感觉、言语障碍或运动症状(所谓的复杂先兆)。广泛的先兆临床谱导致对先兆现象的异质性是否可以由不同的神经相关因素产生的调查,表明复杂 MwA 中视觉皮层兴奋性增加。目的是探讨复杂 MwA 患者是否具有视觉网络连接性变化更明显的特征,以及与简单视觉 MwA 患者相比,功能异常是否可能超出视觉网络,包括复杂 MwA 患者的感觉运动网络。
更新日期:2021-08-12
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