Utilization of Rhenium(I) Polypyridine Complexes Featuring a Dinitrophenylsulfonamide Moiety as Biothiol-Selective Phosphorogenic Bioimaging Reagents and Photocytotoxic Agents,European Journal of Inorganic Chemistry

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Utilization of Rhenium(I) Polypyridine Complexes Featuring a Dinitrophenylsulfonamide Moiety as Biothiol-Selective Phosphorogenic Bioimaging Reagents and Photocytotoxic Agents
European Journal of Inorganic Chemistry ( IF 2.2 ) Pub Date : 2021-08-10 , DOI: 10.1002/ejic.202100680
Guang‐Xi Xu ₁ , Lawrence Cho‐Cheung Lee ₁ , Cyrus Wing‐Ching Kwok ₁ , Peter Kam‐Keung Leung ₁ , Jing‐Hui Zhu ₁ , Kenneth Kam‐Wing Lo _{1,

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Affiliation

The Front Cover shows the combined effort of the 2,4-dinitrophenylsulfonamide (DNPS) and tosylamide flippers in directing the rhenium(I) pinball to hit the glutathione (GSH) triangular slingshots, permitting the targeted imaging of the endoplasmic reticulum and mitochondria; the pinball may also hit the mushroom bumpers to generate singlet oxygen (¹O₂) for photodynamic therapeutic applications (Graphic Design: Mr Michael W.-L. Chiang). More information can be found in the Full Paper by K. K.-W. Lo and co-workers.

中文翻译：

使用具有二硝基苯磺酰胺部分的铼 (I) 多吡啶配合物作为生物硫醇选择性磷光生物成像试剂和光细胞毒性剂

封面展示了 2,4-二硝基苯磺酰胺 (DNPS) 和甲苯磺酰胺鳍状肢在引导铼 (I) 弹球击中谷胱甘肽 (GSH) 三角弹弓方面的共同作用，从而实现内质网和线粒体的靶向成像；弹球也可能撞击蘑菇缓冲器以产生单线态氧 ( ¹ O ₂ ) 用于光动力治疗应用（平面设计：Mr Michael W.-L. Chiang）。更多信息可以在 KK-W 的全文中找到。罗和同事。

更新日期：2021-09-08

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