Adenovirus (AdV) infections are of particular concern in pediatric hematopoietic stem cell transplantation (HSCT) recipients as therapeutic options are limited. Brincidofovir (BCV) is the lipid-conjugated pro-drug of cidofovir (CDV) with oral bioavailability and higher intracellular concentrations of the active drug.

中文翻译：

---

布西多福韦对腺病毒感染儿科干细胞移植受者的疗效


由于治疗选择有限，腺病毒 (AdV) 感染在儿科造血干细胞移植 (HSCT) 受者中尤其令人担忧。布林西多福韦 (BCV) 是西多福韦 (CDV) 的脂质缀合前药，具有口服生物利用度和较高的活性药物细胞内浓度。