To prevent microbial contamination in foods and medical tools, we prepared a novel antibacterial material nano-silver loaded poly(styrene-co-acrylic) (nAg-PSA) composites by in situ reductions. The nAg-PSA was characterized by scanning electron microscope, transmission electron microscopy, energy dispersive X-ray spectroscopy and thermogravimetric analysis. The antibacterial properties of nAg-PSA against Escherichia coli and Staphylococcus aureus were systematically evaluated, and the underlying mechanism was investigated. Results showed that the silver nanoparticles were successfully loaded onto PSA microspheres, highly dispersed on the surface of nAg-PSA nanoparticles. The nAg-PSA nanoparticles all showed significant antibacterial effects, among which nAg-PSA4 had maximum diameters of inhibition zones against the Gram-negative E. coli (1.18 mm) and the Gram-positive S. aureus (1.29 mm), respectively, which closely related to the size and density of silver nanoparticles covered on the surface.

为了防止食品和医疗工具中的微生物污染，我们通过原位还原制备了一种新型抗菌材料纳米银负载聚（苯乙烯-共-丙烯酸）（nAg-PSA）复合材料。nAg-PSA 通过扫描电子显微镜、透射电子显微镜、能量色散 X 射线光谱和热重分析表征。nAg-PSA对大肠杆菌和金黄色葡萄球菌的抗菌作用进行了系统评估，并研究了潜在的机制。结果表明，银纳米粒子成功负载到 PSA 微球上，高度分散在 nAg-PSA 纳米粒子的表面。nAg-PSA纳米颗粒均表现出显着的抗菌作用，其中nAg-PSA4对革兰氏阴性大肠杆菌（1.18 mm）和革兰氏阳性金黄色葡萄球菌（1.29 mm）的抑菌圈直径最大，分别为与覆盖在表面的银纳米粒子的大小和密度密切相关。