The commensal microflora collection known as microbiota has an essential role in maintaining the host's physiological homeostasis. The microbiota has a vital role in induction and regulation of local and systemic immune responses. On the other hand, the immune system involves maintaining microbiota compositions. Optimal microbiota-immune system cross-talk is essential for protective responses to pathogens and immune tolerance to self and harmless environmental antigens. Any change in this symbiotic relationship may cause susceptibility to diseases. The association of various cancers and auto-immune diseases with microbiota has been proven. Here we review the interaction of immune responses to gut microbiota, focusing on innate and adaptive immune system and disease susceptibility.

中文翻译：

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肠道微生物群对免疫系统的影响。


被称为微生物群的共生微生物群在维持宿主的生理稳态方面具有重要作用。微生物群在诱导和调节局部和全身免疫反应中发挥着至关重要的作用。另一方面，免疫系统涉及维持微生物群组成。最佳的微生物群-免疫系统相互作用对于对病原体的保护性反应以及对自身和无害的环境抗原的免疫耐受至关重要。这种共生关系的任何变化都可能导致对疾病的易感性。各种癌症和自身免疫性疾病与微生物群的关联已被证明。在这里，我们回顾免疫反应与肠道微生物群的相互作用，重点关注先天和适应性免疫系统以及疾病易感性。