Conjugated organic polymers (COPs) have been excellent candidates because the conjugated structure occupied π structure that is useful to develop light-emitting materials. However, most COPs emitt weak luminescence owing to the H-aggregation effect. Light-emitting conjugated organic polymers (LCOP-1) possess rich butyl groups anchored in the skeleton to enhance light-emitting activity via reducing the H-aggregation effect. Owing to abundant hydroxyl and nitrogen atoms, LCOP-1 exhibits high sensitivity, selectivity, and fast response to Cu²⁺ ions within 1 min in comparison with the cations of Na⁺, Mg²⁺, Al³⁺, Zn²⁺, Cd²⁺, Ni²⁺, Cr³⁺, Hg²⁺, Fe³⁺, Fe²⁺, Pb²⁺, Co²⁺, etc. The detection limit can be down to nanomolar. Moreover, the sensor exhibits detection toward Cu²⁺ ions via a naked eye colorful change from pale-yellow to yellowish-brown. Furthermore, the light-emitting probe also successfully achieves the detection of Cu²⁺ ions in cells without cytotoxicity, indicating its great potentials in biological function.

中文翻译：

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发光共轭有机聚合物作为用于 Cu2+ 离子检测和细胞成像的高效荧光探针

共轭有机聚合物 (COP) 已成为极好的候选者，因为共轭结构占据π结构，可用于开发发光材料。然而，由于 H 聚集效应，大多数 COP 发出微弱的发光。发光共轭有机聚合物 (LCOP-1) 具有固定在骨架中的丰富丁基，通过减少 H 聚集效应来增强发光活性。由于含有丰富的羟基和氮原子，与 Na ⁺、Mg ²⁺、Al ³⁺、Zn ²⁺、Cd的阳离子相比，LCOP-1在 1 分钟内对 Cu ²⁺离子表现出高灵敏度、选择性和快速响应²⁺ , Ni ²⁺ , Cr³⁺、Hg ²⁺、Fe ³⁺、Fe ²⁺、Pb ²⁺、Co ²⁺等。检测限可低至纳摩尔。此外，该传感器通过肉眼从淡黄色到黄褐色的彩色变化表现出对Cu ²⁺离子的检测。此外，该发光探针还成功实现了对细胞中Cu ²⁺离子的检测，且无细胞毒性，表明其在生物学功能方面具有巨大潜力。