Engagement of LC3-associated phagocytosis (LAP) in response to the uptake of certain particles modulates innate immune responses. Now in Cell Host and Microbe, Akoumianaki et al. (2021) show how a regulatory role of IL-6 on LAP may be at the core of susceptibility to secondary infection during severe sepsis.

中文翻译：

---

LAP 许可

响应于某些颗粒的摄取而参与 LC3 相关吞噬作用 (LAP) 可调节先天免疫反应。现在在细胞宿主和微生物中，Akoumianaki 等人。(2021) 表明 IL-6 对 LAP 的调节作用如何可能是严重败血症期间继发感染易感性的核心。