An oxidative tandem (4+2)-cyclization/aromatization of N-aryl glycine derivatives with electron-deficient alkenes was first achieved using Ru(bpy)₃Cl₂ as a photocatalyst and TBHP as an oxidant in combination with visible-light irradiation by blue LEDs. One-electron oxidation and the following α-deprotonation of glycine derivatives afford α-amino alkyl radicals, which were then trapped by electrophilic maleimides. As an atom-economic and efficient method, a variety of pyrrolo[3,4-c]quinoline-1,3-diones have been obtained in good yields under mild reaction conditions.

中文翻译：

---

甘氨酸衍生物与马来酰亚胺的光催化反极性氧化波瓦洛夫反应

使用 Ru(bpy) ₃ Cl ₂作为光催化剂和 TBHP 作为氧化剂，结合可见光照射，首次实现了N-芳基甘氨酸衍生物与缺电子烯烃的氧化串联 (4+2)-环化/芳构化蓝色 LED。单电子氧化和随后的甘氨酸衍生物的 α-去质子化得到 α-氨基烷基自由基，然后被亲电马来酰亚胺捕获。作为一种原子经济高效的方法，在温和的反应条件下，以良好的收率获得了多种吡咯并[3,4- c ]喹啉-1,3-二酮。