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Single-Cell RNA Sequencing Supports Preferential Bioactivation of Remdesivir in the Liver
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-08-09 , DOI: 10.1128/aac.01333-21
Victoria C Yan 1 , Florian L Muller 2
Affiliation  

A recently published article by Li et al. titled, “Key Metabolic Enzymes in Remdesivir Activation in Lung Cells,” validates the canonical McGuigan enzymes (CES1, CTSA, HINT1) involved in remdesivir’s (RDV’s) bioactivation using bioinformatic and ...

中文翻译:

单细胞 RNA 测序支持 Remdesivir 在肝脏中的优先生物激活

Li等人最近发表的一篇文章。题为“肺细胞中 Remdesivir 激活的关键代谢酶”,使用生物信息学和……
更新日期:2021-09-12
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