People living with HIV are ageing, and a growing number of women living with HIV are entering menopause. Women living with HIV commonly have bothersome vasomotor symptoms and onset of menopause at earlier ages; both factors go on to affect quality of life and systemic health. Vasomotor symptoms and early menopause are both indications for menopausal hormone therapy; however, current evidence suggests that this therapy is seldom offered to women living with HIV. Additionally, women living with HIV have several risks to bone health and are likely to benefit from the bone-strengthening effects of menopausal hormone therapy. We present an assessment of the benefits and risks of menopausal hormone therapy in the context of HIV care and propose a practical approach to its prescription. If considered in the appropriate clinical context with discussion of risks and benefits, menopausal hormone therapy might provide substantial benefits to symptomatic menopausal women living with HIV and improve health-related quality of life.

艾滋病毒感染者正在老龄化，越来越多的艾滋病毒感染者进入更年期。感染 HIV 的女性通常会出现令人烦恼的血管舒缩症状，并且更年期开始较早；这两个因素都会继续影响生活质量和全身健康。血管舒缩症状和更年期提前都是更年期激素治疗的指征；然而，目前的证据表明，这种疗法很少提供给感染艾滋病毒的妇女。此外，感染艾滋病毒的女性对骨骼健康有多种风险，并且可能受益于更年期激素治疗的骨骼强化作用。我们在 HIV 护理的背景下评估了更年期激素治疗的益处和风险，并提出了一种实用的处方方法。