Background/aims To compare the effects of silicone oil tamponade (SOT) to that of gas tamponade (GT) on the best-corrected visual acuity (BCVA) after successful vitrectomy for retinal detachment (RD). Methods A retrospective, multicentre, nationwide study with RD who were registered in the Japan-RD Registry. All cases with RD treated with successful vitrectomy between February 2016 and March 2017 were studied. A propensity score matching was performed using the preoperative findings as covariates to adjust the relevant confounders. The primary outcome was the estimated mean difference of the postoperative BCVA in 6 months between eyes treated with SOT to those treated with GT. Results Of the 3446 cases registered, 2097 cases met the entry criteria. There were 2042 eyes that had GT and 55 eyes that had SOT. Primary success was defined as a reattached retina with no tamponade at 6 months. After propensity score matching, each group contained 40 cases. The preoperative BCVA was 0.966±0.738 logMAR units in the GT group and 1.270±0.945 logMAR units in the SOT group (p=0.177). Six months postoperatively, the BCVA in the GT group was significantly better at 0.309 logMAR units in the GT group than the 0.671 logMAR units in the SOT group (p=0.002). Conclusions Even after successful surgery for RD, eyes that experienced SOT had poorer BCVA than eyes treated with GOT. SOT should be considered cautiously. Precis Propensity score analysis of eyes with rhegmatogenous RD showed that postoperative vision was worse in eyes treated once with silicone oil than with gas even after completely successful surgery. Data are available upon reasonable request. The datasets used during the current study are available from the corresponding author on request. The detailed protocol is published in our earlier paper. Sakamoto T, et al . Japan-Retinal Detachment Registry Report I: preoperative findings in eyes with primary retinal detachment. Jpn J Ophthalmol 2019 doi: 10.1007/s10384- 019-00702-6.

中文翻译：

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通过倾向评分分析成功治疗原发性孔源性视网膜脱离的硅油与气体填塞：日本视网膜脱离登记处

背景/目的 比较硅油填塞 (SOT) 与气体填塞 (GT) 对视网膜脱离 (RD) 玻璃体切除术成功后最佳矫正视力 (BCVA) 的影响。方法 一项回顾性、多中心、全国性的 RD 研究，在 Japan-RD Registry 中注册。研究了 2016 年 2 月至 2017 年 3 月期间成功进行玻璃体切除术治疗的所有 RD 病例。使用术前发现作为协变量进行倾向评分匹配以调整相关混杂因素。主要结果是接受 SOT 治疗的眼睛与接受 GT 治疗的眼睛在 6 个月内术后 BCVA 的估计平均差异。结果在登记的3446例中，2097例符合入组条件。有 2042 只眼睛有 GT 和 55 只眼睛有 SOT。初步成功被定义为在 6 个月时没有填塞的视网膜重新附着。倾向评分匹配后，每组包含40例。GT 组的术前 BCVA 为 0.966±0.738 logMAR 单位，SOT 组为 1.270±0.945 logMAR 单位（p=0.177）。术后 6 个月，GT 组的 BCVA 显着优于 SOT 组的 0.309 logMAR 单位，为 0.309 logMAR 单位（p=0.002）。结论 即使在 RD 手术成功后，接受 SOT 的眼睛的 BCVA 也比接受 GOT 治疗的眼睛差。应谨慎考虑 SOT。对孔源性 RD 眼的 Precis 倾向评分分析表明，即使在完全成功的手术后，用硅油治疗一次的眼的术后视力也比用气体治疗的眼差。可根据合理要求提供数据。当前研究期间使用的数据集可根据要求从相应作者处获得。详细的协议发表在我们早期的论文中。坂本 T 等人。日本-视网膜脱离登记报告 I：原发性视网膜脱离眼的术前发现。Jpn J Ophthalmol 2019 doi：10.1007/s10384-019-00702-6。