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Stem cell therapies in tendon-bone healing.
World Journal of Stem Cells ( IF 4.1 ) Pub Date : 2021-8-10 , DOI: 10.4252/wjsc.v13.i7.753
Yue Xu 1 , Wan-Xia Zhang 1 , Li-Na Wang 1 , Yue-Qing Ming 1 , Yu-Lin Li 1 , Guo-Xin Ni 1
Affiliation  

Tendon-bone insertion injuries such as rotator cuff and anterior cruciate ligament injuries are currently highly common and severe. The key method of treating this kind of injury is the reconstruction operation. The success of this reconstructive process depends on the ability of the graft to incorporate into the bone. Recently, there has been substantial discussion about how to enhance the integration of tendon and bone through biological methods. Stem cells like bone marrow mesenchymal stem cells (MSCs), tendon stem/progenitor cells, synovium-derived MSCs, adipose-derived stem cells, or periosteum-derived periosteal stem cells can self-regenerate and potentially differentiate into different cell types, which have been widely used in tissue repair and regeneration. Thus, we concentrate in this review on the current circumstances of tendon-bone healing using stem cell therapy.

中文翻译:

肌腱骨愈合中的干细胞疗法。

肌腱骨插入损伤如肩袖和前交叉韧带损伤目前非常常见和严重。治疗这种损伤的关键方法是重建手术。这种重建过程的成功取决于移植物融入骨骼的能力。最近,关于如何通过生物方法增强肌腱和骨骼的结合,已经有了大量的讨论。骨髓间充质干细胞 (MSC)、腱干/祖细胞、滑膜来源的 MSC、脂肪来源的干细胞或骨膜来源的骨膜干细胞等干细胞可以自我再生并可能分化成不同的细胞类型,这些细胞类型具有广泛应用于组织修复和再生。因此,
更新日期:2021-08-10
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