Toxoplasma gondii and multiple sclerosis: A systematic review and meta-analysis,European Journal of Neurology

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Toxoplasma gondii and multiple sclerosis: A systematic review and meta-analysis
European Journal of Neurology ( IF 4.5 ) Pub Date : 2021-08-09 , DOI: 10.1111/ene.15055
Calogero Edoardo Cicero ₁ , Francesca Elsa Allibrio ₁ , Loretta Giuliano ₁ , Jaime Luna ₂ , Pierre-Marie Preux ₂ , Alessandra Nicoletti ₁

Affiliation

According to the hygiene hypothesis, infections by agents such as parasites have a protective role against the risk of developing multiple sclerosis (MS). Among parasites, Toxoplasma gondii, an intracellular parasite, showed evidence of a protective effect. This study was undertaken to summarize the available evidence on the association between T. gondii infection and MS.

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