Background

Recent studies suggest that the mortality rate of pulmonary fibrosis (PF) in the U.S. is decreasing. However, the mortality trends and demographic differences of PF among the states have not been evaluated.

Objective

To evaluate PF-related mortality rates and trends in the nine most populated states in the U.S.

Methods

Population-based study using the Multiple Cause of Death Database available through the Centers for Disease Control and Prevention website. PF-related deaths were identified using ICD codes.

Results

From 2004 to 2018, average annual mortality rates ranged from being the lowest in New York (110.8 per 1,000,000) to the highest in North Carolina (195.3 per 1,000,000). The mortality rates showed a decline in the majority of the states and were stable in the other states. The most significant declines were in California and Michigan. The average mortality rates in males were higher than females in all the states (rate ratio ranged from 1.56 in Texas to 1.81 in New York) and the decline in the mortality rates was more pronounced compared to males in most states. The mortality rates in Blacks were lower compared to Whites in all the states (rate ratio ranged from 0.47 in New York to 0.69 in Ohio) and the decline in the mortality rates over the period was more significant than in Whites.

Conclusions

There is substantial variation in mortality rates and mortality trends between states and different demographics. Further studies are needed to evaluate the environmental factors, diagnostic accuracy, and coding practices contributing to these differences.

中文翻译：

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美国人口最多的州之间肺纤维化的死亡率差异

背景

最近的研究表明，美国肺纤维化（PF）的死亡率正在下降。然而，尚未评估各州之间 PF 的死亡率趋势和人口统计学差异。

客观的

评估美国 9 个人口最多的州的 PF 相关死亡率和趋势

方法

使用疾病控制和预防中心网站提供的多种死因数据库进行基于人群的研究。使用 ICD 代码确定与 PF 相关的死亡。

结果

从 2004 年到 2018 年，年平均死亡率从纽约最低（每 100 万人 110.8 人）到北卡罗来纳州最高（每 100 万人 195.3 人）不等。大多数州的死亡率呈下降趋势，其他州则保持稳定。降幅最大的是加利福尼亚州和密歇根州。所有州的男性平均死亡率均高于女性（比率从德克萨斯州的 1.56 到纽约的 1.81 不等），并且与大多数州的男性相比，死亡率的下降更为明显。与所有州的白人相比，黑人的死亡率都较低（比率从纽约的 0.47 到俄亥俄的 0.69），并且在此期间死亡率的下降比白人更显着。

结论

各州和不同人口统计数据之间的死亡率和死亡率趋势存在很大差异。需要进一步的研究来评估导致这些差异的环境因素、诊断准确性和编码实践。