Multiple recent lines of evidence suggest that, at least in some patients, RA-associated autoimmunity and inflammation may originate in the lung (1, 2). However, what exactly is/are the initiating event(s), and the sequence of subsequent events, is not fully defined.

中文翻译：

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肺部炎症、NETosis 和 ACPA 反应的肺部启动：先有鸡还是先有蛋？

最近的多项证据表明，至少在某些患者中，RA 相关的自身免疫和炎症可能起源于肺部 (1, 2)。然而，究竟什么是起始事件，以及后续事件的顺序，并没有完全定义。