Three previously undescribed chlorophenyl glycosides, (2,4,6-trichloro-3-hydroxy-5-methoxyphenyl)methyl β-D-glucopyranoside (1), (2,4-dichloro-3,5-dimethoxyphenyl)methyl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside (2) and 4-chloro-3-methoxy-5-methylphenyl 6-O-(6-deoxy-β-L-mannopyranosyl)-β-D-glucopyranoside (3) were obtained from Lilium regale. The absolute configurations of these new finds were elucidated by comprehensive analyses of spectroscopic data combined with acid hydrolysis derivatization. (2,4-dichloro-3,5-dimethoxyphenyl)methyl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside (2) can inhibit the proliferation of lung carcinoma A549 cells with an IC₅₀ value of 29 μΜ.

中文翻译：

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三种以前未描述的来自百合球茎的氯苯基糖苷

三种以前未描述的氯苯基糖苷，(2,4,6-三氯-3-羟基-5-甲氧基苯基)甲基 β-D-吡喃葡萄糖苷 ( 1 )，(2,4-二氯-3,5-二甲氧基苯基)甲基 6- O -β-D-吡喃葡萄糖基-β-D-吡喃葡萄糖苷( 2 )和4-氯-3-甲氧基-5-甲基苯基6- O- (6-脱氧-β-L-吡喃甘露糖基)-β-D-吡喃葡萄糖苷( 3) ) 是从Lilium regal中获得的。这些新发现的绝对构型是通过光谱数据的综合分析结合酸水解衍生化来阐明的。(2,4-二氯-3,5-二甲氧基苯基)甲基 6 - O -β-D-吡喃葡萄糖基-β-D-吡喃葡萄糖苷 ( 2)可以抑制肺癌A549细胞的增殖，IC ₅₀值为29 μM。