Koninginin W, a New Polyketide from the Endophytic Fungus Trichoderma koningiopsis YIM PH30002,Chemistry & Biodiversity

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Koninginin W, a New Polyketide from the Endophytic Fungus Trichoderma koningiopsis YIM PH30002
Chemistry & Biodiversity ( IF 2.3 ) Pub Date : 2021-08-09 , DOI: 10.1002/cbdv.202100460
Yong-Liang Wang _{1,

2} , Bin-Yuan Hu ₁ , Meng-An Qian ₁ , Zi-Hang Wang ₁ , Jing-Mei Zou _{1,

2} , Xu-Yan Sang _{1,

2} , Lei Li _{1,

2} , Xiao-Dong Luo ₁ , Li-Xing Zhao _{1,

2}

Affiliation

A new compound named koninginin W (1) and four known polyketides (2â€“5) were isolated from endophytic fungus Trichoderma koningiopsis YIM PH30002 of Panax notoginseng. The structures of 1 - 5, including absolute configuration of 1, were elucidated on the detailed analysis of the HR-ESI-MS, 1D and 2D NMR, and X-ray crystallographic data. Koninginin W (1) presented weak antibacterial activity against Escherichia coli, Bacillus subtilis and Salmonella typhimurium.

中文翻译：

Koninginin W，一种来自内生真菌 Trichoderma koningiopsis YIM PH30002 的新聚酮化合物

命名新化合物koninginin W（1）和四个已知聚酮化合物（2 €“ 5）从内生真菌分离木霉koningiopsis的YIM PH30002三七。的结构1 - 5，包括的绝对构型1，分别鉴定在HR-ESI-MS，一维和二维NMR和X-射线晶体学数据的详细分析。Koninginin W( 1 )对大肠杆菌、枯草芽孢杆菌和鼠伤寒沙门氏菌的抗菌活性较弱。

更新日期：2021-09-14

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