Abstract

Natural organic nanoparticle cellulose nanocrystals (CNCs) with good biocompatibility and unique physical and chemical properties have been proved to be promising materials for drug delivery systems. In this study, a CNC with rich. It has the property of modifying dendrimers. The polymer has good biocompatibility and stability. TEM shows that CNC has a good particle size, about 154–200 nm. And after modifying the amine group, the polymer still has good dispersibility. Because CNC-NH₂ has a good size, it can better bypass the human body clearance system and enter cancer cells.

中文翻译：

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pH响应性树枝状聚合物功能化棉纤维素纳米晶体可有效治疗癌症

摘要

具有良好生物相容性和独特物理和化学性质的天然有机纳米颗粒纤维素纳米晶体 (CNCs) 已被证明是用于药物递送系统的有前途的材料。在本研究中，CNC 具有丰富的功能。它具有修饰树枝状聚合物的特性。该聚合物具有良好的生物相容性和稳定性。TEM 显示 CNC 具有良好的粒径，约为 154-200 nm。并且在对胺基进行改性后，聚合物仍具有良好的分散性。由于CNC-NH ₂具有良好的尺寸，它可以更好地绕过人体清除系统并进入癌细胞。