Children undergoing hematopoietic stem cell transplantation (HSCT) are vulnerable to pain due to the intensity and toxicity of this treatment. An instrumental case study design of two qualitative phases was conducted to examine the pain experiences of hospitalized children during HSCT therapy and how contextual factors related to the pediatric HSCT environment influenced their experience of pain. The Social Communication Model of Pain provided the conceptual framework for the study. In Phase 1, semi-structured interviews were conducted with parents of a child undergoing HSCT therapy at two time points. Phase 2 was conducted as a naturalistic observational study of the clinical care provided to children and semi-structured interviews with health-care providers. Children experienced complex and multifaceted pain with physical, psychological, and contextual contributors. Understanding the many factors contributing to the child’s pain experience can inform strategies to improve the management of pain during HSCT therapy.

由于这种治疗的强度和毒性，接受造血干细胞移植 (HSCT) 的儿童很容易感到疼痛。进行了两个定性阶段的工具性案例研究设计，以检查住院儿童在 HSCT 治疗期间的疼痛经历以及与儿科 HSCT 环境相关的背景因素如何影响他们的疼痛经历。疼痛的社会交流模型为研究提供了概念框架。在第一阶段，在两个时间点对接受 HSCT 治疗的孩子的父母进行了半结构化访谈。第 2 阶段是作为对提供给儿童的临床护理的自然观察研究和与医疗保健提供者的半结构化访谈进行的。孩子们经历了身体、心理、和上下文贡献者。了解导致儿童疼痛经历的许多因素可以为改善 HSCT 治疗期间疼痛管理的策略提供信息。