Journal of Neuroimmunology ( IF 2.9 ) Pub Date : 2021-08-08 , DOI: 10.1016/j.jneuroim.2021.577691 Young Gi Min 1 , Woohee Ju 2 , Ye-Eun Ha 2 , Jae-Jun Ban 3 , Seol Ah Lee 2 , Jung-Joon Sung 1 , Je-Young Shin 2
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Massive vaccination against COVID-19 has become a global priority. Simultaneously, concerns regarding the safety of vaccines are growing. We describe two patients who developed sensory Guillain-Barre syndrome (GBS) shortly after the first dose of the ChAdOx1 vaccine. We also summarize 12 published cases of GBS after ChAdOx1 vaccination, highlighting their unique clinical and paraclinical features. We propose a possible association between the risk of GBS and the ChAdOx1 vaccine and recommend surveillance for GBS following vaccination. Population-based studies are needed to determine causality and whether specific subpopulations are susceptible.
中文翻译：
ChAdOx1 nCov-19 疫苗后的感觉格林巴利综合征：两例报告和文献复习
针对 COVID-19 的大规模疫苗接种已成为全球优先事项。与此同时，人们对疫苗安全性的担忧也在增加。我们描述了两名在第一剂 ChAdOx1 疫苗接种后不久出现感觉性格林-巴利综合征 (GBS) 的患者。我们还总结了 12 例已发表的 ChAdOx1 疫苗接种后 GBS 病例，突出了它们独特的临床和临床旁特征。我们提出 GBS 风险与 ChAdOx1 疫苗之间可能存在关联，并建议在接种疫苗后监测 GBS。需要基于人群的研究来确定因果关系以及特定亚群是否易感。
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