Direct and rapid mass spectrometry (MS) analysis is desired for many applications including environmental monitoring, forensic analysis, chemical and biological defense, and point-of-care testing. However, sample pretreatment is often necessary for analyzing targets from complex matrices using MS due to ion suppression. To achieve rapid MS analysis calls for simple and efficient solutions for sample processing and ionization. Here, a simple sample pretreatment and ionization workflow is reported, which achieves sample desalting, enrichment, and ionization on a single glass slide.

中文翻译：

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在全疏水载玻片上集成样​​品脱盐、富集和电离，用于直接质谱分析

许多应用都需要直接和快速的质谱 (MS) 分析，包括环境监测、法医分析、化学和生物防御以及即时检测。然而，由于离子抑制，使用 MS 分析复杂基质中的目标通常需要样品预处理。为了实现快速 MS 分析，需要简单高效的样品处理和电离解决方案。在这里，报告了一个简单的样品预处理和电离工作流程，它在单个载玻片上实现了样品脱盐、富集和电离。