Background and Purpose: The short-term benefits of endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) have been widely documented, yet there is limited evidence to show that this is sustained in the long term. We aimed to determine whether the benefit of EVT on functional outcome at 3 months is maintained at 12 months and the factors correlating with functional independence and quality of life. Methods: Data for analysis came from a prospective registry of consecutive patients undergoing EVT at a single Comprehensive Stroke Center (Oct 2018–Sep 2019). A phone interview was conducted for 12-month patient outcomes. Functional outcome was assessed by the modified Rankin Scale (mRS). Quality of life was determined by return to usual place of residence, work, or driving and calculation of a health utility index using the European Quality of Life-5 Dimensions questionnaire (EQ-5D-3L). Results: Of the 151 patients who underwent EVT during the study period, 12-month follow-up was available for 145 (96%). At 12 months, 44% (n = 64) of patients were functionally independent (mRS 0–2) compared to 48% at 3 months. Mortality at 12 months was 26% compared to 17% at 3 months. Significant predictors of functional independence at 12 months were younger age and lower baseline National Institutes of Health Stroke Scale. Better quality of life significantly correlated with return to usual place of residence and driving. Conclusion: Three-month functional independence was sustained at 12 months, indicating that EVT remains beneficial for patients with AIS in the longer term.
Cerebrovasc Dis Extra 2021;11:81–86

中文翻译：

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卒中血管内血栓切除术对功能结果的益处在 12 个月时持续

背景和目的：血管内血栓切除术 (EVT) 对急性缺血性卒中 (AIS) 的短期益处已被广泛记录，但只有有限的证据表明这种益处可以长期持续。我们旨在确定 EVT 对 3 个月时功能结果的益处是否在 12 个月时保持不变，以及与功能独立性和生活质量相关的因素。方法：用于分析的数据来自在单一综合卒中中心（2018 年 10 月至 2019 年 9 月）接受 EVT 的连续患者的前瞻性登记。对 12 个月的患者结果进行了电话采访。功能结果通过改良的 Rankin 量表 (mRS) 进行评估。生活质量是通过返回通常居住、工作或驾驶的地方，并使用欧洲生活质量 5 维度问卷 (EQ-5D-3L) 计算健康效用指数来确定的。结果：在研究期间接受 EVT 的 151 名患者中，145 名 (96%) 可获得 12 个月的随访。在 12 个月时，44% ( n= 64) 的患者功能独立 (mRS 0–2)，而 3 个月时为 48%。12 个月时的死亡率为 26%，而 3 个月时为 17%。12 个月时功能独立性的重要预测因素是年龄较小和基线美国国立卫生研究院卒中量表较低。更好的生活质量与返回常住地和驾驶显着相关。结论：在 12 个月时持续了 3 个月的功能独立性，表明 EVT 从长期来看对 AIS 患者仍然有益。
Cerebrovasc Dis Extra 2021；11:81–86