Aged memory-impaired cynomolgus monkeys had significantly lower levels of cerebrospinal amyloid (Aβ₄₂) and serum testosterone compared with young animals and non–memory-impaired controls. Our findings confirm similar findings in the human and substantiate the usefulness of the cynomolgus monkey as a spontaneous model for aging-associated senile dementia of the Alzheimer type.

中文翻译：

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与年龄相关的认知障碍与雄性食蟹猴 (Macaca fascicularis) 的血清睾酮浓度和淀粉样蛋白 42 的脑脊液水平低有关

与年轻动物和非记忆障碍对照组相比，老年记忆障碍食蟹猴的脑脊髓淀粉样蛋白 (Aβ ₄₂ ) 和血清睾酮水平显着降低。我们的研究结果证实了人类中的类似发现，并证实了食蟹猴作为阿尔茨海默型衰老相关老年痴呆症的自发模型的有用性。