Background:The relationship between nutritional status and the incidence or prognosis of atrial fibrillation (AF) has been reported, but no studies have described the relationship between the outcomes of AF catheter ablation (CA) and nutritional status as assessed by various scoring tools. We aimed to verify the hypothesis that preoperative nutritional status is associated with arrhythmia recurrence after CA for AF.

Methods and Results:We evaluated 913 patients (age, 67±10 years; men, 72%; paroxysmal AF, 56%) who underwent CA for AF between November 2011 and November 2017. Patients were systematically followed with an endpoint of atrial tachyarrhythmia recurrence, the predictive value of which was compared among 3 scoring tools (Controlling Nutritional Status [CONUT] score / Geriatric Nutritional Risk Index [GNRI] / Prognostic Nutritional Index [PNI]). Patients were divided into normal nutrition (CONUT <2 [n=637] / GNRI >98 [n=836] / PNI >38 [n=910]) and undernutrition (CONUT ≥2 [n=276] / GNRI ≤98 [n=77] / PNI ≤3 [n=3]) groups. AF recurred in 274 patients (mean follow-up, 2.3±0.8 years). The AF recurrence rate was higher in patients with undernutrition than in those with normal nutrition (CONUT/GNRI) status. Multivariate Cox regression analysis identified undernutrition status (GNRI ≤98) as an independent predictor of atrial tachyarrhythmia recurrence.

Conclusions:The AF recurrence rate after CA was higher in patients with undernutrition than in those with normal nutrition as stratified by the nutrition scoring tools.

背景：营养状况与心房颤动 (AF) 的发生率或预后之间的关系已有报道，但没有研究描述 AF 导管消融 (CA) 的结果与各种评分工具评估的营养状况之间的关系。我们旨在验证术前营养状况与 AF CA 后心律失常复发相关的假设。

方法和结果：我们评估了 2011 年 11 月至 2017 年 11 月期间因房颤接受 CA 的 913 名患者（年龄，67±10 岁；男性，72%；阵发性房颤，56%）。对患者进行系统随访，终点为房性快速性心律失常复发，预测值其中在 3 种评分工具（控制营养状况 [CONUT] 评分 / 老年营养风险指数 [GNRI] / 预后营养指数 [PNI]）之间进行了比较。患者分为营养正常（CONUT <2 [n=637] / GNRI >98 [n=836] / PNI >38 [n=910]）和营养不足（CONUT ≥2 [n=276] / GNRI ≤98 [ n=77] / PNI ≤3 [n=3]) 组。AF 在 274 名患者中复发（平均随访时间为 2.3±0.8 年）。营养不良患者的 AF 复发率高于营养正常 (CONUT/GNRI) 状态的患者。

结论：根据营养评分工具分层，营养不良患者的 CA 后 AF 复发率高于营养正常的患者。