Still's disease is a rare systemic inflammatory disease with frequent but generally mild liver involvement. The most common cause of acute liver failure in western countries is drug-induced liver injury, while it has rarely been reported in subjects suffering from Still’s disease. We report a case of a young woman presenting with SD reactivation in pregnancy and acute liver failure after delivery with a possible triggering role of drug induced liver injury. The prompt recognition of Still's disease reactivation allowed early introduction of steroid therapy and resolution of the clinical picture. We discuss potential factors precipitating ALF in this case, and implications for the diagnosis and management of such patients.

中文翻译：

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妊娠期斯蒂尔病复发引起的急性肝功能衰竭：病例报告和 DILI 可能触发作用的讨论

斯蒂尔病是一种罕见的全身性炎症性疾病，常见但通常轻微的肝脏受累。在西方国家，急性肝衰竭最常见的原因是药物性肝损伤，而斯蒂尔病患者中很少有报道。我们报告了一名年轻女性的病例，她在怀孕期间出现 SD 再激活，并在分娩后出现急性肝功能衰竭，可能触发药物性肝损伤。对斯蒂尔病重新激活的及时识别使得能够及早引入类固醇治疗并解决临床问题。我们讨论了本例中引发 ALF 的潜在因素，以及对此类患者的诊断和治疗的影响。