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OMIP 078: A 31-parameter panel for comprehensive immunophenotyping of multiple immune cells in human peripheral blood mononuclear cells
Cytometry Part A ( IF 2.5 ) Pub Date : 2021-08-06 , DOI: 10.1002/cyto.a.24490
Takuto Nogimori 1, 2 , Yuko Sugawara 1, 3 , Masaya Higashiguchi 1, 4 , Hirotomo Murakami 1, 4 , Hirofumi Akita 1, 4 , Shokichi Takahama 1 , Satoshi Tanaka 1, 3 , Takuya Yamamoto 1, 2, 5, 6
Affiliation  

This 31-parameter panel was developed for simultaneously measuring multiple immune cell populations including T cells, B cells, natural killer cells, dendritic cells, monocytes, and hematopoietic progenitor cells in human peripheral blood mononuclear cells. This panel enables the capture of individual immune dynamics and assessments of single-cell changes in the immune system that are associated with aging and diseases. This panel includes markers to separate the differentiation status of each cell population and might be applicable to studies of infectious and autoimmune diseases, as patient samples are usually limited in volume and require an analysis system that provides a relatively large amount of information.

中文翻译:

OMIP 078:用于对人外周血单个核细胞中的多种免疫细胞进行综合免疫表型分析的 31 参数面板

该 31 参数面板用于同时测量人外周血单核细胞中的多种免疫细胞群,包括 T 细胞、B 细胞、自然杀伤细胞、树突细胞、单核细胞和造血祖细胞。该面板能够捕获个体免疫动态并评估与衰老和疾病相关的免疫系统中的单细胞变化。该面板包括用于区分每个细胞群分化状态的标记物,可能适用于传染病和自身免疫性疾病的研究,因为患者样本通常数量有限,需要一个提供相对大量信息的分析系统。
更新日期:2021-09-01
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