Strain M2^T was isolated from the beach of Cuxhaven, Wadden Sea, Germany, in course of a program to attain new producers of bioactive natural products. Strain M2^T produces litoralimycin and sulfomycin-type thiopeptides. Bioinformatic analysis revealed a potential biosynthetic gene cluster encoding for the M2^T thiopeptides. The strain is Gram-stain-positive, rod shaped, non-motile, spore forming, showing a yellow colony color and forms extensively branched substrate mycelium and aerial hyphae. Inferred from the 16S rRNA gene phylogeny strain M2^T affiliates with the genus Streptomonospora. It shows 96.6% 16S rRNA gene sequence similarity to the type species Streptomonospora salina DSM 44593 ^T and forms a distinct branch with Streptomonospora sediminis DSM 45723 ^T with 97.0% 16S rRNA gene sequence similarity. Genome-based phylogenetic analysis revealed that M2^T is closely related to Streptomonospora alba YIM 90003 ^T with a digital DNA-DNA hybridisation (dDDH) value of 26.6%. The predominant menaquinones of M2^T are MK-10(H₆), MK-10(H₈), and MK-11(H₆) (> 10%). Major cellular fatty acids are iso-C_16:0, anteiso C_17:0 and C_18:0 10-methyl. The polar lipid profile consisted of diphosphatidylglycerol phosphatidyl glycerol, phosphatidylinositol, phosphatidylcholine, phosphatidylethanolamine, three glycolipids, two unknown phospholipids, and two unknown lipids. The genome size of type strain M2^T is 5,878,427 bp with 72.1 mol % G + C content. Based on the results obtained from phylogenetic and chemotaxonomic studies, strain M2^T (= DSM 106425 ^T = NCCB 100650 ^T) is considered to represent a novel species within the genus Streptomonospora for which the name Streptomonospora litoralis sp. nov. is proposed.

菌株 M2 ^T是从德国瓦登海的库克斯港海滩分离出来的，该项目旨在获得生物活性天然产品的新生产者。菌株 M2 ^T产生利托利霉素和磺霉素型硫肽。生物信息学分析揭示了编码 M2 ^T硫肽的潜在生物合成基因簇。该菌株为革兰氏染色阳性、杆状、不运动、形成孢子，呈黄色菌落颜色并形成广泛分枝的底物菌丝体和气生菌丝。从 16S rRNA 基因系统发育菌株推断 M2 ^T隶属于链单孢菌属。它显示出 96.6% 的 16S rRNA 基因序列与模式物种Strepomomonospora salina的相似性DSM 44593  ^T与Streptomonospora sediminis DSM 45723  ^T形成一个独特的分支，具有 97.0% 的 16S rRNA 基因序列相似性。基于基因组的系统发育分析表明，M2 ^{T与白链单胞}菌YIM 90003  ^T密切相关，数字 DNA-DNA 杂交 (dDDH) 值为 26.6%。M2 ^T的主要甲基萘醌是 MK-10(H ₆ )、MK-10(H ₈ ) 和 MK-11(H ₆ ) (> 10%)。主要的细胞脂肪酸是 iso-C _16:0、 anteiso C _17:0和 C _18:010-甲基。极性脂质谱由二磷脂酰甘油磷脂酰甘油、磷脂酰肌醇、磷脂酰胆碱、磷脂酰乙醇胺、三种糖脂、两种未知磷脂和两种未知脂质组成。^{M2 T}型菌株的基因组大小为 5,878,427 bp，G + C 含量为 72.1 mol %。根据从系统发育和化学分类学研究中获得的结果，菌株 M2 ^T (= DSM 106425  ^T  = NCCB 100650  ^T ) 被认为代表链单孢菌属中的一个新物种，其名称为Strepomonospora litoralis sp。十一月 被提议。