Ratio of Propylene Glycol to Glycerol in E-Cigarette Reservoirs Is Unchanged by Vaping As Determined by 1H NMR Spectroscopy,Chemical Research in Toxicology

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Ratio of Propylene Glycol to Glycerol in E-Cigarette Reservoirs Is Unchanged by Vaping As Determined by 1H NMR Spectroscopy
Chemical Research in Toxicology ( IF 3.7 ) Pub Date : 2021-08-04 , DOI: 10.1021/acs.chemrestox.1c00208
Paul J Kerber ₁ , Anna K Duell ₁ , David H Peyton ₁

Affiliation

E-cigarette liquids (e-liquids) contain propylene glycol (PG) and/or glycerol (GL) to deliver flavorants/nicotine. It has recently been suggested that the PG:GL ratio in e-cigarette reservoirs changes during vaping, leaving almost entirely GL after aerosolizing much of a 30:70 PG:GL mixture. To evaluate this directly, we analyzed e-liquids from e-cigarettes before and after aerosolization using 4 different coils, and aerosol samples generated using high and low e-liquid levels. The PG:GL ratios of initial and final e-liquids and aerosol samples were comparable. This is important because a large change in e-liquid composition could substantially alter the aerosol profile during a vaping session.

中文翻译：

1H NMR 光谱测定电子烟储液器中丙二醇与甘油的比例不会因吸电子烟而发生变化

电子烟液（e-liquid）含有丙二醇（PG）和/或甘油（GL）以提供香料/尼古丁。最近有人提出，电子烟储液器中的 PG:GL 比例在吸食过程中会发生变化，在雾化大部分 30:70 PG:GL 混合物后几乎完全留下 GL。为了直接评估这一点，我们使用 4 种不同的线圈分析了雾化前后电子烟的电子烟液，以及使用高和低电子烟液水平生成的气雾剂样本。初始和最终电子烟液和气雾剂样品的 PG:GL 比率具有可比性。这很重要，因为电子烟液成分的巨大变化可能会大大改变电子烟使用过程中的气溶胶分布。

更新日期：2021-08-16

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