Effects of co-administration of vitamin E and lithium chloride on chronic constriction injury-induced neuropathy in male Wistar rats: Focus on antioxidant and anti-inflammatory mechanisms,Pain Practice

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Effects of co-administration of vitamin E and lithium chloride on chronic constriction injury-induced neuropathy in male Wistar rats: Focus on antioxidant and anti-inflammatory mechanisms
Pain Practice ( IF 2.5 ) Pub Date : 2021-08-05 , DOI: 10.1111/papr.13064
Kingsley Dominic Esu ₁ , Ahmed Olalekan Bakare ₁ , Bamidele Victor Owoyele ₁

Affiliation

This study investigated the antinociceptive effects of co-administration of lithium chloride (LiCl) and vitamin E (Vit E) on chronic constriction injury (CCI)-induced peripheral neuropathy in male Wistar rats. It further explored the anti-inflammatory and neuroprotective properties of LiCl and Vit E, which may be complementary to the antinociceptive effects of the two substances.

中文翻译：

维生素E和氯化锂联合给药对雄性Wistar大鼠慢性压迫性损伤引起的神经病变的影响：关注抗氧化和抗炎机制

本研究调查了氯化锂 (LiCl) 和维生素 E (Vit E) 共同给药对雄性 Wistar 大鼠慢性压迫性损伤 (CCI) 诱导的周围神经病变的镇痛作用。它进一步探讨了 LiCl 和 Vit E 的抗炎和神经保护特性，这可能与这两种物质的抗伤害作用互补。

更新日期：2021-08-05

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