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Identifying and targeting the Achilles heel of a recalcitrant cancer
Science Translational Medicine ( IF 17.1 ) Pub Date : 2021-08-04 , DOI: 10.1126/scitranslmed.abj6946 Triparna Sen 1, 2
中文翻译:
识别和靶向顽固性癌症的致命弱点
更新日期:2021-08-05
Science Translational Medicine ( IF 17.1 ) Pub Date : 2021-08-04 , DOI: 10.1126/scitranslmed.abj6946 Triparna Sen 1, 2
Affiliation
Targeting replication stress response proteins in small cell lung cancer activates the innate immune cGAS-STING pathway leading to augmentation of immunotherapy’s antitumor response.
中文翻译:
识别和靶向顽固性癌症的致命弱点
靶向小细胞肺癌中的复制应激反应蛋白可激活先天免疫 cGAS-STING 通路,从而增强免疫疗法的抗肿瘤反应。