Vanadium pentoxide (V₂O₅) featured with open-framework structure and various oxidation states is regarded as the most promising cathode of aqueous zinc-ion batteries (ZIBs), whereas sluggish Zn²⁺ diffusion kinetics and poor structural stability plague its further application. Herein, the oxygen defects have been introduced into V₂O₅ (V₂O₅-O_d), the experimental studies and first-principles calculations reveal the oxygen defects can enlarge the interlayer spacing (7.58 Å) and significantly lower the Zn²⁺ diffusion energy barrier (0.72 eV), leading to favorable Zn²⁺ migration path and fast reactive kinetics. Moreover, a narrower bandgap (0.45 eV) and lower charge transfer resistance are obtained in V₂O₅-O_d, thus accelerating the electron transportation and improving the Zn²⁺ storage performance (427.3 mAh/g at 0.1 A/g). In addition, the internal structure of V₂O₅ is well-maintained owing to the greatly reduced formation energy of V₂O₅-O_d (55.04 eV), contributing to outstanding cycling stability (92.1% after 5,000 cycles at 20 A/g), outperforming numerous reported cathodes. Moreover, the pouch cell with V₂O₅-O_d delivers admirable electrochemical performance and modular integration capabilities, suggestive of its excellent practical viability. Therefore, this research highlights the great potential of oxygen defects in designing advanced electrodes and offers a guideline for exploring the working mechanism of defective electrode materials.

五氧化二钒（V ₂ O ₅）具有开放骨架结构和多种氧化态，被认为是最有前途的水性锌离子电池（ZIBs）正极，而缓慢的Zn ²⁺扩散动力学和较差的结构稳定性阻碍了其进一步应用. 在此，氧缺陷被引入到 V ₂ O ₅ (V ₂ O ₅ -O _d ) 中，实验研究和第一性原理计算表明氧缺陷可以扩大层间距 (7.58 Å) 并显着降低 Zn ^{2 +}扩散能垒 (0.72 eV)，导致有利的 Zn ²⁺迁移路径和快速反应动力学。此外，在V ₂ O ₅ -O _d中获得更窄的带隙（0.45 eV）和更低的电荷转移电阻，从而加速电子传输并提高Zn ²⁺存储性能（427.3 mAh/g，0.1 A/g）。此外，由于 V ₂ O ₅ -O _d (55.04 eV) 的形成能大大降低，V ₂ O ₅的内部结构得到很好的维护，有助于出色的循环稳定性（在 20 A/5,000 次循环后达到 92.1% g)，优于许多报道的正极。此外，具有 V ₂ O ₅ -O的软包电池_d提供令人钦佩的电化学性能和模块化集成能力，表明其出色的实用可行性。因此，这项研究突出了氧缺陷在设计先进电极方面的巨大潜力，并为探索有缺陷的电极材料的工作机制提供了指导。