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Open, engage, bind, translocate: The multi-level dynamics of bacterial protein translocation
Structure ( IF 4.4 ) Pub Date : 2021-08-05 , DOI: 10.1016/j.str.2021.07.003
Wei Chen 1 , Elizabeth A Komives 1
Affiliation  

The bacterial Sec translocase transports unfolded proteins across membranes. In this issue of Structure, Krishnamurthy et al. (2021) report a nexus of conformational dynamics in the translocase motor protein, SecA. Their findings shed light on the Sec activation mechanism and suggest a general role for multi-level dynamics in protein functions.



中文翻译:

打开、接合、结合、易位:细菌蛋白质易位的多层次动力学

细菌 Sec 转位酶跨膜运输未折叠的蛋白质。在本期结构中,Krishnamurthy 等人。(2021) 报告了易位酶运动蛋白 SecA 中构象动力学的关系。他们的发现阐明了 Sec 激活机制,并表明了蛋白质功能中多级动力学的一般作用。

更新日期:2021-08-05
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